Bone Densitometry and Osteogenesis Imperfecta
One of the most consistent features of the skeletal defect in
osteogenesis imperfecta (OI) is low
bone density, a major reason for excess skeletal fragility and fractures in this disorder.
Bone densitometry (also known as a
bone density test or
bone density scan) can be helpful in assessing skeletal development in
children with osteogenesis imperfecta and determining the likelihood of fractures. It can also be useful to assess the possible effects of injuries, illness and/or medications in patients with OI. Bone densitometry allows physicians to assess the effects of treatments designed to build up bone mass or prevent bone loss.
While bone densitometry measurements may be useful in the management of anyone with OI, individuals with Type I osteogenesis imperfecta usually benefit most. They have the longest life span among people with OI and will be faced with the bone loss associated with
menopause, immobilization, medications (such as cortisone-like drugs), etc. Thus, bone density measurements may be most useful in managing these problems, particularly menopause.
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