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Didronel Dosage

Didronel Dosing for Paget's Disease

The recommended starting Didronel dose for treating Paget's disease of bone is 5 mg per kg of body weight (about 2.3 mg per pound) once daily for up to six months. If necessary, your healthcare provider may increase your dose up to 20 mg per kg (about 9 mg per pound) once daily. Didronel doses higher than 10 mg per kg (about 4.5 mg per pound) should be given for a shorter period of time (three months or less).
If necessary, you may be retreated with Didronel after at least 90 days after the initial treatment.

General Information on Dosing With Didronel

Considerations for people taking Didronel include the following:
  • The medication comes in tablet form. It is taken by mouth every day for a period of time (usually three to six months, depending on several factors).
  • Take Didronel on an empty stomach first thing in the morning. Do not eat for two hours before or after taking the drug. Many foods interact with Didronel, decreasing its absorption into the body (making it less effective).
  • Swallow Didronel tablets whole with a full glass of plain water (not any other beverage).
  • Try to stay upright for 30 minutes after taking Didronel, as this can help prevent irritation to your esophagus.
  • Do not take vitamins, minerals, or antacids that contain calcium, iron, magnesium, or aluminum for two hours after taking Didronel (see Didronel Drug Interactions).
  • It is best to take Didronel at the same time each day to maintain an even level of the medication in your blood.
  • For the medication to work properly, it must be taken as prescribed.
  • If you are unsure about anything related to Didronel or your Didronel dosage, please talk with your doctor, nurse, or pharmacist. Do not stop taking the drug without first discussing it with your healthcare provider.
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Didronel for Paget's Disease

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