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Jakafi and Breastfeeding

The manufacturer of Jakafi (ruxolitinib) recommends that women not use this drug while nursing. Although Jakafi does pass through breast milk in rats, it is unknown whether it passes through human breast milk or if it would cause problems in a nursing infant. If you are breastfeeding while using Jakafi, watch for problems in your child, such as vomiting, difficulty feeding, or excessive crying.

Can Breastfeeding Women Take Jakafi?

Jakafi™ (ruxolitinib) is a prescription medication approved for the treatment of myelofibrosis, a condition characterized by scarring of the bone marrow (the spongy tissue in the center of some bones). It is unknown if Jakafi passes through breast milk in humans.

More Information About Jakafi and Breastfeeding

In animal studies, Jakafi was shown to pass through the breast milk of rats. However, it is unknown whether the medicine also passes through human breast milk, as it has not been studied in breastfeeding women. Due to this lack of information, it is possible that breastfeeding while taking Jakafi could expose an infant to the medication, along with the risks associated with Jakafi use.
The manufacturer of Jakafi recommends the drug not be used in women who are nursing. Jakafi is associated with potentially serious side effects, including an increased risk for infections, bleeding, and anemia.
If your healthcare provider recommends Jakafi while you are nursing, make sure to watch for any problems in your child. Contact your child's healthcare provider if your child experiences any possible Jakafi side effects, such as:
  • Unusual bruising or bleeding
  • Fever
  • Coughing
  • Unusual tiredness
  • Excessive crying
  • Diarrhea
  • Vomiting
  • Difficulty feeding.
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Jakafi Medication Information

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