Patents and exclusivity rights currently prevent a generic Jakafi (ruxolitinib) from being manufactured in the United States. The first patent is expected to expire in December 2027, which would be the earliest date that a generic version might become available. However, certain circumstances, such as lawsuits or other patents for new uses of the drug, could delay this date.
Can I Buy Generic Jakafi?
Jakafi™ (ruxolitinib) is a prescription medication approved to treat a disease of the bone marrow known as myelofibrosis. It comes as a tablet that is usually taken twice a day.
Jakafi is made by DSM Pharmaceuticals, Inc., for Incyte Corporation. It is currently protected from generic competition by patents and exclusivity rights that have not yet expired.
When Will a Generic Version Be Available?
The first patent for Jakafi is set to expire in December 2027. This is the earliest predictable date that a generic version could become available.
However, other circumstances could come up to extend or shorten this exclusivity period. This could include such things as lawsuits or other patents for specific Jakafi uses. Once the drug goes off-patent, there may be several companies that manufacture a generic Jakafi drug.
Is Ruxolitinib a Generic Jakafi?
No -- ruxolitinib is the active ingredient in Jakafi, not a generic version of it. What can be confusing is that the active ingredient of a drug is often referred to as the "generic name." The generic name is different from a generic version of a medicine.
In order for there to be a generic version of a medicine, the original medicine must have gone off-patent, and another company besides the original manufacturer must make the product.
Written by/reviewed by: Kristi Monson, PharmD;Arthur Schoenstadt, MD
Last reviewed by: KristiMonson, PharmD;
List of references (click here):
Jakafi [package insert]. Wilmington, DE: Incyte Corporation;2011 November.
Food and Drug Administration, Center for Drug Evaluation and Research. Electronic orange book: approved drug products with therapeutic equivalence evaluations. FDA Web site. Available at: http://www.fda.gov/cder/ob/. Accessed February 21, 2012.
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