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Jakafi is a medicine licensed for the treatment of a certain type bone marrow disorder called myelofibrosis. It is designed to help reduce the size of an enlarged spleen and relieve symptoms of myelofibrosis, such as night sweats and bone pain. This medicine comes as a tablet that is taken twice daily. Potential side effects include dizziness, headaches, and bruising.
What Is Jakafi?Jakafi™ (ruxolitinib) is a prescription medication approved to treat a disorder of the bone marrow known as myelofibrosis. Myelofibrosis is characterized by scarring of the bone marrow. Jakafi is used to treat people who are considered intermediate-risk or high-risk, based on their expected survival. It belongs to a class of medicines known as kinase inhibitors.
How Does Jakafi Work?
Clinical EffectsClinical studies have been done to determine the effectiveness of Jakafi in people with myelofibrosis who had enlarged spleens and needed treatment because of symptoms. In these studies, Jakafi was shown to reduce spleen size and relieve myelofibrosis symptoms, including:
- Abdominal (stomach) discomfort
- Night sweats
- Bone or muscle pain.