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Osteogenesis Imperfecta Symptoms

Some common symptoms of osteogenesis imperfecta may include bones that fracture easily, hearing loss, a tendency to bruise easily, and several other symptoms related to problems with collagen formation. Osteogenesis imperfecta (OI) symptoms will vary from patient to patient, depending on which type of the disorder the person has. Because of this reason, it is also extremely difficult to predict the symptoms or complications a person with osteogenesis imperfecta should expect.

An Overview of Osteogenesis Imperfecta Symptoms

Osteogenesis imperfecta symptoms vary significantly according to type, so it is very difficult to predict what kind of symptoms or complications a person will have.
The characteristic osteogenesis imperfecta symptoms also vary greatly from person to person, even among people with the same type of the disorder, and even within the same family. In addition, not all symptoms are evident in each case.

Common Osteogenesis Imperfecta Symptoms

Symptoms of osteogenesis imperfecta typically include:
  • Bones that fracture easily
  • Short stature
  • Hearing loss
  • Discolored, brittle teeth
  • Blue sclera (blue color in the whites of the eyes)
  • Skeletal deformities of limbs, chest, and skull
  • Scoliosis (curvature of the spine)
  • Respiratory difficulties
  • Weak muscles
  • Excessive sweating
  • Constipation
  • Tendency to bruise easily
  • Loose joints and ligaments
  • High-pitched voice.
Please keep in mind that very few people with osteogenesis imperfecta exhibit all of these symptoms, and that the severity of each symptom can vary tremendously between individuals.
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